The Benefits of Using Ketamine Infusion Therapy for Severe Depression

The Benefits of Using Ketamine Infusion Therapy for Severe Depression

Why try Ketamine Infusion Therapy?

If a person has severe depression, Ketamine Infusion Therapy is the right choice for treatment. Many antidepressant medications and substances have been available over the past few decades, however many sufferers still experience major depression despite their intensive treatment regimen. Ketamine Infusion Therapy, though, has proven to be more effective than other treatments. Although the method is still relatively new, many patients who have received Ketamine Infusion Therapy have noticeably higher improvement rates compared to other treatments.  Ketamine infusions for depression is an outpatient procedure, and they do not need to be admitted to a hospital. The procedure takes around an hour in total.  Ketamine has garnered much attention for its rapid antidepressant effects that peak in just twenty-four hours after an infusion. Since Ketamine is such a fast-acting substance, patients and physicians both find it to be much more beneficial than traditional treatment options.

What effect can Ketamine Infusion Therapy have on Severe Depression?

Although there is no clear way to determine how a person will react to the treatment since every person is different, patients that have shown symptoms since childhood and patients with severe depression onset later in life have both shown noticeable improvements. There have been many instances of the treatments greatly improving the patient’s symptoms. Usually signs of improvement are apparent after the first treatment. It is recommended to have six infusions in a twelve-day timeframe. This way the ketamine in the system will encourage new dendrite and synapse growth, thereby addressing the physical causes of depression. It is noted that depression relief lasts around a few months before a booster infusion is needed.  This treatment can potentially be a lifesaving factor in prevention of suicide. Since feeling hopeless or helpless is usually a key factor prompting suicide, the infusions can effectively eliminate these negative emotions. Ketamine Infusion Therapy is proven to be effect on both unipolar and bipolar depression as well as most other treatment-resistant depressive disorders.

Is Ketamine Infusion Therapy safe?

Yes, Ketamine has been used on people for around fifty years as an anesthetic, though treatment for depression is still in its early stages. Researchers are currently looking for ways to make the drug more easily available including tablet or inhalant forms. For right now use of Ketamine must be monitored closely by a medical professional. Setting up a regular schedule of Ketamine Infusion Therapy treatments is completely safe and low risk, as infusion therapy uses very low doses of Ketamine. Many people regard receiving Ketamine Infusion Therapy treatments as one of the best decisions they ever made. Mental health is as important as the physical health. Chemical imbalances in the brain are just as harmful as an injury that can be seen by the eye. Many people have reported an enhanced social life and regaining their sense of humor. Family relationships especially have improved greatly. Research continues to improve protocols and enhance the effectiveness of ketamine infusion therapy.


Ionescu, Dawn F, et al. “A Single Infusion of Ketamine Improves Depression Scores In Patients With Anxious Bipolar Depression.” Bipolar Disorders 17.4 (2015): 438-443.

Al Jurdi, Rayan k., and Sanjay J. Mathew. “Ketamine For Treatment-Resistant Unipolar Depression: Current Evidence.” Psychiatric Times 31.9 (2014): 1-7. CINAHL Complete.

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