Ketamine Infusion: Unbelievable Effects on Patients Suffering from Severe Depression

Ketamine Infusion: Unbelievable Effects on Patients Suffering from Severe Depression

The use of ketamine in treating severe depression is being considered as one of the most significant advances in mental health community during the past half century.

Though some people might be wary of subjecting their loved ones to ketamine infusions, due to its stigma as a recreational drug, ketamine has shown immediate relief in the treatment of depression. For most patients and families affected by this condition, ketamine therapy is expressed as  “nothing short of a miracle”.

Expert opinion

The beneficial results are seen immediately after receiving the infusion. One can imagine its impact on those suffering with suicidal tendencies. By treating these patients instantly with infusion therapy, ketamine healthcare providers can actually help save lives.

According to Enrique Abreu, who has been administering ketamine to patients suffering with depression since 2012, the astounding response rate and the 75% level of effectiveness, highlights ketamine worthiness in treating this chronic condition. When prescription medicine and behavioral therapy have failed, ketamine has provided patients with a new hope with a more effective response rate.

Short history of Ketamine

Before ketamine started being used on humans, it was administered to horses as a veterinary sedative. Later on, people began abusing this sedative and it became known as the street drug “Special K”. In large doses, it is known to induce a drug like stupor and transient hallucinations.

After the 1960’s, it was used in lower doses for operating on children with broken bones. Ketamine was also used in place of morphine on soldiers injured during combat and patients suffering with severe burns.

Ketamine infusions today

During the past decade extensive research has been carried out on ketamine and its effects. The major reason why ketamine has gained so much popularity is its ease of administration, fewer side effects and quick results. Unlike traditional medications which make may take three to eight weeks to show results, ketamine infusion offers relief immediately.

It is administered intravenously in a much lower dosage than when it is used as an anesthetic. This lessens the possibility of adverse side effects and addiction.

According to L Allison McInnes, a psychiatrist at Kaiser Permanent Clinic, when patients do not respond to medicinal drugs, they have no choice but to undergo electroshock therapy and transcranial stimulation. In these cases, ketamine infusions worked in alleviating depressive symptoms and were less invasive than intensive therapies.

In 2010, a study published in Science suggested ketamine works by stopping the production of proteins with NMDA receptor functionality. By doing this, ketamine enables the brain to overproduce the synaptic signaling proteins found in the prefrontal cortex of the brain- the area involved in cognitive, emotional, and social function. By inhibiting the production of the NMDA receptor proteins and enabling the production of synaptic signaling proteins, new synapses are created in the brain. This intricate system results in peacefulness and antidepressant effects within patients suffering from mental disorders.

There is a limited amount of healthcare centers in America which use ketamine for treating depression and other chronic conditions. Though more research is being carried out to determine the long term effects of ketamine, it is considered an exciting discovery and one which can actually change the way depression is treated.









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